Category: Progress update

Leveraging transcriptomics for antisense oligonucleotide drug discovery

Advances in massive parallel sequencing provide an unprecedented ability to survey the transcriptome. Sequencing-based approaches allow studying globally not only RNA abundance and splice isoforms, but also structure and accessibility, binding of proteins, as well as rates of turnover—all of

Posted in COAT, Oligoinformatics, Progress update, Research

Physical technology transfer

< p>As one of the first technology transfers in COAT, Jeppe and Lukazs from KU visited Santaris to obtain a number of cell lines. Working with the same cell lines at both Santaris and KU allows more comparable results. Lukazs

Posted in Progress update