Blog Archives

PhD positions at the Department of Biology, University of Copenhagen

We are now hiring two new PhD students to join the COAT team in the Section for Bioinformatics and RNA Biology PhD at the Department of Biology, University of Copenhagen. You can find the announcement here.

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Posted in COAT, Education, Research, Sequencing

How to efficiently read in large bedgraph files in R

This post is a bit R programming-technical, but I have spent quite some time finding a solution, so I thought I would share it anyway. First some background. One of the factors that might affect the potency of an antisense

Posted in Education, Oligoinformatics, Sequencing

RNA BBQ

On Tuesday August 21st we will be BARBECUING RNA of several different kinds (with and without chloroplasts)!  Everyone (even remotely..) affiliated with the summer course on RNA are welcome. But registration is required in order for us to know how much stuff

Posted in Education, Social

The transcriptome ‐ from functional RNAs to RNA drugs

We now (finally) have the program for the symposium on the 24th of August in the Lundbeckfond  Auditorium, Copenhagen Biocenter. The symposium is arranged together with Center for non-coding RNA in Technology and Health and sponsored by the The Danish Council

Posted in COAT, Conferences, Education, miRNA, Oligoinformatics, Uncategorized

Ph.D. summer school closed for applications

The Ph.D. course: “RNA – from sequencing and computational analysis to RNA drugs” , August 20-24, 2012 is now full and we therefore no longer accept incoming applications.

Posted in COAT, Education, Sequencing

Summer school on RNA biology and drugs

There is an exciting PhD course to take place from the 20th to the 24th of August in Copenhagen. The course will cover the following topics: parallel sequencing technologies, microRNA Biology and ‐targeting, protein‐RNA interactions, RNA structure and antisense oligonucleotide

Posted in COAT, Education, miRNA, Sequencing

How vast is the chemical space of RNA drugs?

Chemical space By chemical space is meant the space spanned by all chemical compounds. As of January 2012, there are more than 64 million organic and inorganic substances reported in the scientific literature (link). This is, however, still only a vanishing

Posted in Education, Oligoinformatics

RNA world hypothesis

All life, and therefore also life based on RNA, must be able to decrease or at least maintain its entropy. The functional repertoire of RNA needs to be quite varied for this to work. The RNA world hypothesis can therefore

Posted in Education

Project: MicroRNA Masters project at Santaris Pharma

Santaris offers a Masters project on microRNA mechanisms in metabolic diseases starting in Sept 2011. Santaris Pharma is a biopharmaceutical company that develops innovative RNA-targeted medicines based on its proprietary locked nucleic acid (LNA) drug platform. The Company’s LNA oligonucleotide

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Posted in Education

Project: High-throughput probing and prediction of RNA structure to facilitate RNA drug design

UPDATE: This project is filled. Background At the Center for Computational and Applied Transcriptomics (COAT), experimental and computational methods are being used to investigate RNA structure and RNA-protein interactions on a transcriptome wide scale to enable the design of effective

Posted in Education, Oligoinformatics
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