Category: drugs

RNA antisense drugs in the pipelines

We give an overview of the antisense drug discovery and development programs that are in the pipeline for RNA targeted medicine. It is based on manual collection of data from company websites and clinicaltrials.gov. Main author is Stine Møllerud. A

Posted in business, drugs

Toxicity of antisense oligonucleotides can be predicted

When antisense oligonucleotides are dosed systemically in rodents, injury to the liver is sometimes seen. The liver is one of the organs that accumulate the most oligonucleotides, and this may be part of the reason. However, some oligonucleotides can accumulate

Posted in COAT, drugs, Oligoinformatics, Research